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DeCS
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Descriptor English:
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Receptor Tyrosine Kinase-like Orphan Receptors
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Descriptor Spanish:
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Receptores Huérfanos Similares al Receptor Tirosina Quinasa
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Descriptor Portuguese:
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Receptores Órfãos Semelhantes a Receptor Tirosina Quinase
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Tree Number:
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D08.811.913.696.620.682.725.400.093
D12.776.543.750.060.233
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Definition English:
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A family of cell surface receptors that were originally identified by their structural homology to neurotropic TYROSINE KINASES and referred to as orphan receptors because the associated ligand and signaling pathways were unknown. Evidence for the functionality of these proteins has been established by experiments showing that disruption of the orphan receptor genes results in developmental defects. |
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Indexing Annotation English:
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do not confuse with ORPHAN NUCLEAR RECEPTORS
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History Note English:
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2010
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Allowable Qualifiers English:
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Record Number:
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53614
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Unique Identifier:
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D057050
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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